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Peer Responses · Respond in a respectful manner to another student’s post. Agree or disagree with some of the student’s

Peer Responses

· Respond in a respectful manner to another student’s post. Agree or disagree with some of the student’s statements and add some novel idea or expand on one of the student’s ideas.

· Each response post should include a minimum of 250 words of actual text (i.e., the 250 word minimum does

not
include your reference)

· At least 1 outside, empirical/peer-reviewed reference should be integrated in your response post (your textbook and the lecture do

not
count as an outside source). Failure to include an outside source will result in a grade of 0.

· Correct APA formatting of citations/references is required and part of your grade

Peer: Thamires

The nervous system consists of two subsystems: the central nervous system (CNS), which includes the brain and spinal cord, and the peripheral nervous system (PNS), involving cranial nerves and spinal nerves (Garret & Hough, 2022). Oligodendrocyte cells are glial cells that produce the myelin around neurons in the brain and spinal cord (Garret & Hough, 2022). In contrast, Schwann cells are glial cells that produce the myelin around neurons outside the brain and spinal cord (Garret & Hough, 2022).

Wei et al. (2024) suggest that regeneration is a procedure where damaged neuron axons are restored and reconnected with pre-damaged target tissues, reestablishing synaptic activity and physiological functions in the specific injured area. However, the regeneration ability of glial cells varies; the peripheral nerve system’s regeneration capacities are more remarkable as it possesses exceptional plasticity of the Schwann cells (Wei et al., 2024). The central nervous system, on the other hand, does not have the same abilities since adults do not encounter the chemical and molecular structures that facilitate and direct neuronal growth (Garret & Hough, 2022). Therefore, according to Wei et al. (2024), Schwann cells have a substantial capacity to phagocytose myelin debris compared to oligodendrocytes in the central nervous system.

Cell therapy has shown significant progress in using living cells to restore damaged tissues (Wei et al., 2024). Wei et al. (2024) state that the transplantation of Schwann cells and nerve scaffolds can stimulate the rehabilitation of damaged nerves. Moreover, Schwann cells might also promote the maintenance of spared neural tissues, restore lesion cavities, and establish the growth of motor and sensory axons (Wei et al., 2024).

References

Garrett, B. & Hough, G. (2022).
Brain & behavior: An introduction to behavioral neuroscience (6th ed.). Sage Publications.

Wei, C., Guo, Y., Ci, Z., Li, M., Zhang, Y., & Zhou, Y. (2024). Advances of Schwann cells in peripheral nerve regeneration: From mechanism to cell therapy.
Biomedicine & Pharmacotherapy, 175, 116645.

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